Publications by authors named "J Tsuboi"
Article Synopsis
- Hereditary hemochromatosis (HH) is a serious iron-storage disorder that can cause significant organ damage, and HH type 3 is linked to mutations in the TFR2 gene, which is rare in Asia.
- A 69-year-old Japanese woman with joint pain and liver issues was found to have high iron levels and a novel homozygous mutation in her TFR2 gene, identified through genetic testing.
- After treatment with phlebotomy, her arthritis and liver enzyme levels improved, marking the first documented case of this specific mutation in an HH type 3 patient.
Article Synopsis
- A study compared inside stent (IS) and conventional stent (CS) for preoperative biliary drainage in patients with localized perihilar cholangiocarcinoma (LPHC) using data from 56 patients.
- Results showed that the IS group had significantly fewer instances of recurrent biliary obstruction (RBO), longer time to RBO, and needed fewer stent replacements compared to the CS group.
- Additionally, patients with IS experienced shorter hospital stays and lower overall costs preoperatively and postoperatively, indicating potential benefits for both patients and the healthcare system.
A 54-year-old woman presented with an elevated esophageal lesion. Computed tomography (CT) and magnetic resonance imaging revealed a mass in the pancreatic head. Endoscopic ultrasound (EUS) showed a well-defined, round, hypoechoic mass, which was considered lymph node enlargement.
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- The study investigates risk factors leading to painful colonoscopies and extended cecal intubation times specifically in female patients.
- Key findings highlight that women with sigmoid colon diverticulosis have a higher likelihood of experiencing pain during the procedure, while better tools (small-caliber colonoscopes) can reduce pain.
- Additionally, inadequate bowel preparation is linked to longer cecal intubation times, suggesting that preparation quality is crucial for a smoother procedure.