Publications by authors named "J Treichel"
Article Synopsis
- The study investigates the effectiveness of high-resolution nerve ultrasound (HRUS) in diagnosing polyneuropathy caused by the chemotherapy drug vincristine.
- Twelve patients undergoing vincristine treatment and twelve healthy controls participated, with measurements taken at various intervals, including nerve cross-sectional areas (CSAs), neuropathy scores, and nerve conduction studies.
- Results indicated that while overall CSA at nerve entrapment sites increased alongside clinical symptoms, HRUS did not show significant changes at individual nerve sites, highlighting that clinical exams are key for early detection of vincristine-induced polyneuropathy.
Background And Purpose: The role of high-resolution nerve ultrasound (HRUS) and corneal confocal microscopy (CCM) in the early detection of taxane-induced polyneuropathy (TIPN) is unclear. The present prospective longitudinal controlled observational pilot study estimates the role of HRUS and CCM in the early diagnosis of TIPN in breast cancer patients.
Methods: Fifteen breast cancer patients receiving paclitaxel and 15 healthy age matched controls were included.
Article Synopsis
- Latino families are at a higher risk for type 2 diabetes, making lifestyle interventions crucial for prevention, which this study aims to address through a culturally-informed approach.
- The research will involve 132 Latino families participating in a 16-week program that includes nutrition education and physical activity, with assessments of glucose tolerance and quality of life at the start and after several months.
- The study is expected to reveal the effectiveness of a family-oriented diabetes prevention strategy, contributing valuable insights for supporting high-risk Latino communities in managing their health.
Vagus nerve cross-sectional area decreases in Parkinson's disease.
Parkinsonism Relat Disord
September 2023
Introduction: Morphological alterations of the vagus nerve (VN) in Parkinson's disease (PD) are discussed controversially. Several studies reported no difference in VN cross-sectional area (CSA) in PD patients in nerve ultrasound, others found a reduced CSA interpreted as atrophy of the VN and involvement of the dorsal nucleus of VN.
Methods: In a prospective comparative cross-sectional study, CSA of the VN bilaterally and the right ulnar nerve, clinical PD scales, non-motor symptoms and autonomic tests were compared between 49 PD patients and 24 healthy controls.
Within the SulfoSYS (Sulfolobus Systems Biology) project, the effect of temperature on a metabolic network is investigated at the systems level. Sulfolobus solfataricus utilizes an unusual branched ED (Entner-Doudoroff) pathway for sugar degradation that is promiscuous for glucose and galactose. In the course of metabolic pathway reconstruction, a glucose dehydrogenase isoenzyme (GDH-2, SSO3204) was identified.
View Article and Find Full Text PDF