Study of the preparation, characterization, and solubility of lidocaine complexed with 5-sulfosalicylic acid dihydrate.

Objective: This study was to prepare solid dispersions of lidocaine (Lid) with 5-sulfosalicylic acid dihydrate (SSA) by freeze-drying (freeze-dried [FD] Lid/SSA = 1/1) and to evaluate their physical properties.

Methods: Here, we evaluated the physicochemical properties and solubility of solid dispersions of Lid and SSA prepared by freeze-drying (freeze-dried [FD] Lid/SSA = 1/1).

Results: Differential scanning calorimetry measurements showed that after freeze-drying, the endothermic peak due to Lid melting, the dehydration peak, and the endothermic peak due to SSA melting disappeared.

Sensitive U/U Isotopic Analysis of Trace Uranium in Safeguards Environmental Samples Using Multicollector Inductively Coupled Plasma Mass Spectrometry.

A sensitive analytical technique was developed for determining a 10 level low U/U ratio using multicollector inductively coupled plasma mass spectrometry. This analytical technique can determine the subnanogram amount of uranium in safeguards environmental samples. To increase the sensitivity of the U/U ratio, (1) the feed solution was concentrated to one-tenth of that in the conventional method and (2) data acquisition was started from the beginning of the solution uptake until all of the solution was exhausted.

Microbially formed Mn(IV) oxide as a novel adsorbent for removal of Radium.

Radioactivity of Ra isotopes in natural waters is of serious concern. Control of Ra concentrations in tailings ponds, which store waste from U ore extraction processes, is an important issue in mill tailings management. In this study, we tested microbially formed Mn(IV) oxide as an adsorbent for removal of Ra in water treatment.