Does the degree of cell lesion in breast cancer after inductive chemotherapy have any prognostic value?

During 1991 and 1992, 77 patients with breast cancer were treated with induction chemotherapy using the CMFV and FAC protocols at the Lublin Oncological Centre. The degree of cancer cell damage in the specimens obtained postoperatively was evaluated by microscopy. Complete or substantial damage of neoplastic cells was found in 29% of the cases; whereas minimal to no damage was found in 71% of specimens.

[Laryngeal cancer in siblings].

A rare case is described of laryngeal cancer in brother and sister. There have been as yet 21 similar cases in literature reports. The role of habits is discussed as well as certain familial proneness, rarely observed in this type of neoplasm.