Publications by authors named "J Tod Guidry"

Article Synopsis
  • * A study surveyed 1,068 parents from Catholic, Evangelical, or Mainline Protestant backgrounds, finding that 72.3% of children had received the vaccine, with no significant differences in uptake across the denominations.
  • * Key factors affecting vaccination decisions included perceived benefits of the vaccine, barriers, self-efficacy, and communication from healthcare providers, highlighting the importance of fostering better provider-parent interactions and collaboration with religious groups to improve vaccine acceptance.
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Background: Ang-II (angiotensin II) impairs the function of the antihypertensive enzyme ACE2 (angiotensin-converting enzyme 2) by promoting its internalization, ubiquitination, and degradation, thus contributing to hypertension. However, few ACE2 ubiquitination partners have been identified, and their role in hypertension remains unknown.

Methods: Proteomics and bioinformatic analyses were used to identify ACE2 ubiquitination partners in the brain, heart, and kidney of hypertensive C57BL6/J mice of both sexes.

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Article Synopsis
  • Chromosome 22q11.2 deletion syndrome (22q11.2DS) is linked to high rates of anxiety and psychosis, influenced by the COMT gene, which regulates important neurotransmitters.
  • A study examined the relationship between COMT gene variations and anxiety as well as stress hormone responses in 30 affected children and adolescents.
  • The findings revealed that those with the active COMTval allele experienced higher anxiety levels, while there was no significant difference in cortisol levels, indicating that COMT variations affect sympathetic stress responses more than hypothalamic ones.
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