Publications by authors named "J Th van Eijk"
Background: Biomarkers of neuronal and axonal damage (serum neurofilament light (sNfL) and serum glial fibrillary acidic protein (sGFAP)) may provide insight into the aetiology of natalizumab wearing-off symptoms (WoSs).
Objectives: We investigated the longitudinal association between and predictive value of sNfL and sGFAP and the occurrence of WoS in MS patients treated with natalizumab.
Methods: We performed longitudinal measurements of sNfL and sGFAP in NEXT-MS trial participants who completed a questionnaire about WoS.
Article Synopsis
- Cardiac fibrosis is a key indicator of poor long-term outcomes in heart transplant patients, and this study examined its clinical determinants and biomarkers using cardiac magnetic resonance imaging (CMR).
- Researchers studied 48 heart transplant recipients, focusing on factors like donor-recipient weight mismatch and how it correlates with types of cardiac fibrosis.
- The findings revealed that weight mismatch is linked to both focal and interstitial fibrosis, with B-type natriuretic peptide (BNP) being the only biomarker associated with interstitial fibrosis.
Article Synopsis
- * Four key themes emerged: unclear responsibilities among stakeholders, concerns about safety and patient security, the importance of involving users in the development and adoption processes, and the idea that telemedicine complements traditional care rather than replaces it.
- * While telemedicine shows promise for heart failure management, its limited adoption is tied to existing care systems; enhancing collaboration and establishing clear roles could improve confidence and effectiveness in using telemedicine.
Article Synopsis
- Ventilation is really important during CPR because it helps get oxygen into the body, but there are still many questions about how to do it best.
- This review talks about the problems faced when trying to ventilate someone during cardiac arrest and what we need to know about how to keep their airways open and give the right amount of air.
- It also looks at tools that can help with breathing during CPR and suggests things we should study more in the future to improve CPR techniques.
Article Synopsis
- Telemedicine shows promise in managing heart failure (HF), but studies yield mixed results, making it difficult to form clear guidelines.
- A scoping review of 15 randomized controlled trials (RCTs) with varied HF patient subgroups revealed inconsistent findings on which patients benefit most from telemedicine.
- Differences in subgroup definitions, study demographics, and the need for ongoing real-world evidence highlight the importance of continuous monitoring to optimize telemedicine strategies in HF management.