Levodopa, methylmalonic acid, and neuropathy in idiopathic Parkinson disease.

Objective: Peripheral neuropathy (PN) is thought to be coincidental in patients with idiopathic Parkinson disease (IPD). We sought to examine the prevalence of PN in a population of IPD patients and a potential relationship to levodopa use and fasting methylmalonic acid (MMA) levels.

Methods: In a prospective cohort study, IPD patients randomly selected from a comprehensive database were compared to control subjects regarding the presence and severity of PN using clinical and electrophysiological measures.

Mobile phones, in combination with a computer locator system, improve the response times of emergency medical services in central London.

Introduction: The aim of this study was to determine whether mobile phones and mobile phone locating devices are associated with improved ambulance response times in central London.

Patients And Methods: All calls from the London Ambulance Service database since 1999 were analysed. In addition, 100 consecutive patients completed a questionnaire on mobile phone use whilst attending the St Thomas's Hospital Emergency Department in central London.

Exercise-associated hyponatraemia after a marathon: case series.

Objectives: To review the presentation, treatment and response of those runners from the London Marathon who presented to St Thomas' Hospital with exercise induced hyponatraemia.

Design: Observational case series.

Setting: St Thomas' Hospital, a tertiary hospital situated near the finish line of the 2003 London Marathon.