Publications by authors named "J Tennenbaum"
[Big hype about ChapGPT in medicine : Is it something for rhythmologists? What must be taken into consideration?].
Herzschrittmacherther Elektrophysiol
September 2023
ChatGPT, a chatbot based on a large language model, is currently attracting much attention. Modern machine learning (ML) architectures enable the program to answer almost any question, to summarize, translate, and even generate its own texts, all in a text-based dialogue with the user. Underlying technologies, summarized under the acronym NLP (natural language processing), go back to the 1960s.
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- The spleen plays a key role in filtering blood cells and supporting immune defense, with red pulp clearing damaged red blood cells and white pulp producing antibodies to fight specific infections.
- Acquired impairment of spleen function (hyposplenism) can increase vulnerability to infections, particularly from encapsulated bacteria, as well as raise risks for thrombosis and pulmonary hypertension.
- Sickle cell disease frequently leads to functional asplenia early in life, along with serious complications like hypersplenism and acute splenic sequestration, necessitating a better understanding of spleen function and related pathophysiology.
Article Synopsis
- Ischemic stroke can occur in patients with clonal hypereosinophilic syndrome caused by the FIP1L1-PDGFRA fusion, which is responsive to the drug imatinib.
- A study analyzed 16 male patients with a history of ischemic stroke and eosinophilia, finding a high incidence of bilateral infarctions and a significant proportion of strokes with unclear causes.
- Treatment with imatinib showed promising results, with a low recurrence rate of strokes over a median follow-up period of 4.5 years, suggesting that this syndrome should be considered in unexplained stroke cases.