Publications by authors named "J Taton"

Article Synopsis
  • Seasonal malaria chemoprevention (SMC) has been implemented in Guinea since 2015 to reduce malaria incidence in children aged 3-59 months, targeting areas with high malaria transmission.
  • A study comparing 14 districts showed that SMC districts had significantly lower rates of malaria test positivity and uncomplicated malaria incidence compared to non-SMC districts over the years.
  • Overall, the introduction of SMC demonstrated a positive impact on reducing severe malaria rates across all age groups, reinforcing its effectiveness as part of malaria intervention strategies.
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Background: Seasonal malaria chemoprevention (SMC) has become a critical intervention for malaria prevention and control. There is a growing interest to generate evidence that health campaigns such as SMC can be leveraged for integration or co-administration of other health efforts such as nutritional supplements, immunizations, or vitamin A.

Objective: We conducted a pilot study to assess whether nutrition assessments could be integrated into existing SMC programming in two districts in Guinea.

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Intermittent preventive treatment with sulfadoxine-pyrimethamine (SP) is recommended to prevent malaria in pregnancy. Treatment coverage, particularly for three or more doses, is dependent on pregnant women attending antenatal care (ANC) services as scheduled. The StopPalu project pilot tested short message services (SMSs) to remind women of upcoming ANC visits in the Conakry and Kindia regions of Guinea.

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This review presents the advances in the molecular biology and the pathophysiology of insulin resistance with emphasis on disturbances in cellular glucose transport. New scientific information about the structure and function of glucotransporters from the GLUT4 and SLGT families underline their significance in endocrinopathies and metabolic disease pathogenesis as related to insulin resistance. The new discoveries in this area also contribute to a better understanding of the regulation of insulin receptor and post-receptor reactivity by hormones and by drugs.

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The normalization of cellular glucose assimilation is the basic aim of metabolic therapy in type 2 diabetes mellitus (T2DM). It requires parallel changes in the process of cellular glucose transport (CGT). This review presents the pathophysiological and clinical outlines of CGT.

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