Monodentate Alkoxy/Aryloxy Anchored Yttrium Dihydrides; Anticipated Outcomes and Surprises.

The synthesis, characterization, and solid-state structure of bulky alkoxy- and aryloxy-supported yttrium polynuclear hydrides are reported. Hydrogenolysis of the supertrityl alkoxy anchored yttrium dialkyl, Y(OTr*)(CHSiMe)(THF) () (Tr* = tris(3,5-di--butylphenyl)methyl), resulted in the clean conversion to the tetranuclear dihydride, [Y(OTr*)H(THF)] (). X-ray analysis revealed a highly symmetrical structure (̅ site symmetry) with the four Y atoms located on the corners of a compressed tetrahedron, each bonded to an OTr* and tetrahydrofuran (THF) ligand and the cluster held together by four face-capping, μ-H, and four edge-bridging, μ-H, hydrides.

Development of an alarm symptom-based risk prediction score for localized oesophagogastric adenocarcinoma (VIOLA score).

Background: Gastroesophageal adenocarcinoma is a major contributor to global disease burden with poor prognosis even in resectable, regionally limited stages. Feasible prognostic tools are crucial to improve patient management, yet scarce.

Patients And Methods: Disease-related symptoms, patient, tumour, treatment as well as laboratory parameters at initial diagnosis and overall survival (OS) of patients with stage II and III gastroesophageal adenocarcinoma, who were treated between 1990 and 2020 at the Medical University of Vienna, were evaluated in a cross-validation model to develop a feasible risk prediction score.

Synthesis and Structure of Alkaline Earth Bis{hydrido-tris(3,5-diisopropyl-pyrazol-1-yl)borate} Complexes: Ae(Tp) (Ae = Mg, Ca, Sr, Ba).

The synthesis and structural characterization of Ae(Tp) (Ae = Mg, Ca, Sr, Ba; Tp = hydrido-tris(3,5-diisopropyl-pyrazol-1-yl)borate) are reported. In the crystalline state, the alkaline earth metal centers are six-coordinate, even the small Mg ion, with two κ-,',''-Tp ligands, disposed in a bent arrangement (B···Ae···B < 180°). However, contrary to the analogous Ln(Tp) (Ln = Sm, Eu, Tm, Yb) compounds, which all exhibit a bent-metallocene structure close to symmetry, the Ae(Tp) compounds exhibit a greater structural variation.

Crystal structure of tri-benzyl-bis-(tetra-hydro-furan-κ)lutetium(III).

In the title compound, [Lu(CH)(CHO)] (), the Lu ion is coordinated by three benzyl and two tetra-hydro-furan ligands. Two of the benzyl groups are bonded in a classical η-fashion through the methyl-ene the -carbon atom of the benzyl ligand in addition to bonding through the methyl-ene C atom, resulting in a modified trigonal-bipyramidal coordination geometry about the Lu center.

Formation and structural characterization of a europium(II) mono(scorpionate) complex and a sterically crowded pyraza-bole.

The reaction of EuI(THF) with potassium hydro-tris-(3,5-diiso-propyl-pyrazol-yl)borate (K[HB(3,5- pz)] (= KTp , pz = pyrazol-yl) in a molar ratio of 1:1.5 resulted in extensive ligand fragmentation and formation of the europium(II) mono(scorpionate) complex bis-(3,5-diisopropyl-1-pyrazole)[hydro-tris-(3,5-diiso-propyl-pyrazol-yl)borato]iodido-europium(II), [Eu(CHBN)I(CHN)] or (Tp )(3,5- pzH)EuI, , in high yield (78%). As a typical by-product, small amounts of the sterically crowded pyraza-bole derivative -4,8-bis-(3,5-diiso-propyl-pyrazol-1-yl)-1,3,5,7-tetra-iso-propyl-pyraza-bole, CHBH or -{(3,5- pz)HB(μ-3,5- pz)}, , were formed.