Publications by authors named "J Taillard"
Article Synopsis
- Clozapine is effective for treatment-resistant schizophrenia but can cause significant side effects, notably excessive daytime sleepiness, which is a form of hypersomnolence.
- A systematic review examined how clozapine affects objective measures of hypersomnolence, analyzing six studies using various testing methods like polysomnography (PSG).
- Initial findings showed clozapine led to longer sleep times and quicker sleep onset, but these effects did not last beyond 4-6 weeks, indicating a need for further long-term research on sleep patterns and wakefulness in clozapine-treated patients.
Article Synopsis
- The study aimed to identify factors predicting ongoing driving risks related to sleepiness in patients with obstructive sleep apnea (OSA) undergoing continuous positive airway pressure (CPAP) treatment.
- Researchers analyzed data from over 5,300 patients, assessing incidents of near-misses and accidents before and after at least 90 days of CPAP therapy.
- Findings revealed that ongoing sleepiness while driving and poor treatment adherence (less than 4 hours per night) significantly increased the likelihood of near-misses and accidents, highlighting the need for thorough follow-ups by health professionals.
Background And Objectives: Sleepiness in patients with obstructive sleep apnea (OSA) is associated with accidental and economic burden, as well as cardiovascular risk. Despite OSA treatment, 10-28 % of patients report residual sleepiness. Its determinants, as well as those of objective impaired alertness remain poorly known.
View Article and Find Full Text PDFAssessing chronotype is essential in clinical and research environments, but the Munich ChronoType Questionnaire (MCTQ), a widely utilised tool, is not available in French. Therefore, we carried out an observational monocentric study to validate the French MCTQ against the sleep diary for sleep schedules, the Morningness-Eveningness Questionnaire (MEQ) for chronotype, and polysomnography measures. We utilised the mid-sleep point on free days (MSF), adjusted for sleep debt (MSFsc), to gauge morningness/eveningness.
View Article and Find Full Text PDFObjective: To assess the association between sleep irregularity, anxiety, and depression while controlling for other sleep dimensions and using a longitudinal design.
Methods: Longitudinal cohort study which started in April 2020 during the first French lockdown in the general population. Follow-up questionnaires were completed in June 2020, a period without lockdown measures.