Broadband hyperspectral LiDAR with a free-running gigahertz dual-comb supercontinuum.

Hyperspectral LiDAR (HSL) enables the simultaneous acquisition of the surface geometry and spectral signatures of remote natural targets, making it valuable for various applications such as material probing, automated point cloud segmentation, and vegetation health monitoring. We present a first proof-of-concept study of a broadband dual-comb HSL system based on a 1 GHz dual-comb supercontinuum (SC). The SC spans from 820 to 1300 nm, generated via coherent spectral broadening of a free-running single-cavity dual-comb oscillator at 1053 nm in a single nonlinear photonic crystal fiber.

Characterizing the SARS-CoV-2 antibody response and associations with patient factors: Serological profiling of participants enrolled in the GENCOV study.

Introduction: The GENCOV study sought to evaluate serological differences between individuals with differing COVID-19 severity and outcomes. We assessed the SARS-CoV-2 antibody response of GENCOV participants cross-sectionally 1-, 6-, and 12-months following COVID-19 diagnosis to identify patient factors associated with more robust and durable humoral immune responses.

Materials And Methods: COVID-19 patients and a control cohort of vaccinated infection-naïve participants were recruited at hospital sites across the Greater Toronto Area in Ontario, Canada.

Midpregnancy Placental Growth Factor Screening and Early Preterm Birth.

Importance: Early preterm birth (ie, at less than 34 weeks' gestation) confers a high risk for adverse health outcomes, yet no universal screening strategy exists, preventing targeted delivery of effective interventions.

Objective: To evaluate the ability of midpregnancy placental growth factor (PlGF) screening to identify pregnancies at highest risk for early preterm birth.

Design, Setting, And Participants: This prospective cohort study was conducted at an urban, tertiary care center from 2020 to 2023.