Publications by authors named "J TINOCO"
Objective: To analyze the scientific production on Advanced Practice Nursing based on dissertations and theses published in Brazil.
Method: A bibliometric study, with a descriptive approach based on documents, carried out in the Coordination for the Improvement of Higher Education Personnel Theses and Dissertations Bank, Scientific Electronic Library Online, Virtual Health Library, Latin American and Caribbean Literature in Health Sciences and institutional repositories, from October to November 2023.
Results: Of the 25 scientific productions identified, 16 are dissertations and nine are theses.
Introduction: A positive surgical margin (R1 resection) is a relevant risk factor for local recurrence in patients with pancreatic ductal adenocarcinoma of the pancreas (PDAC). An intraoperative liquid biopsy (ILB) based on tumor cell mobilization could help to detect R1 resection intraoperatively.
Objective: To evaluate the potential role of the intraoperative circulating tumor cells (CTCs) and cluster mobilization on the R0/R1 detection.
Challenges and Opportunities for Adult Vaccine Coverage: Insights for Healthcare Professionals Focusing on Herpes Zoster in Mexico.
Vaccines (Basel)
December 2024
Herpes zoster (HZ) is a common disease in older adults and immunocompromised patients, and is frequently associated with long-term complications that impact quality of life. Fortunately, more than one vaccine against HZ is now available in Mexico. Two expert consensus groups discussed adult vaccination strategies in Mexico, focusing on HZ in older adults and immunocompromised individuals; their insights are reported here.
View Article and Find Full Text PDFThe repurposing of statins as neuroprotective agents and/or anti-brain tumor drugs is limited by challenges in brain bioavailability and systemic off-target effects. Therefore, improved and targeted delivery of statins to the brain is necessary. This study aimed to develop a high-strength liquid formulation of the poorly soluble prodrug simvastatin for intranasal administration, as a strategy to achieve high brain concentrations of the prodrug and/or its active form, tenivastatin.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates two surgical approaches (no-touch vs. superior mesenteric artery) in patients undergoing pancreatoduodenectomy for pancreatic ductal adenocarcinoma, focusing on circulating tumor cells during surgery.
- *Patients were randomly assigned to each group, and samples were taken to measure tumor cell activity at different surgical stages.
- *Results showed no significant differences in tumor cell mobilization or metastasis-free survival between the two approaches, but patients with tumor cell clusters mobilized during surgery had a higher rate of distant metastases within the first year.