Indomethacin reduces lung adenoma number in A/J mice.

The effects of indomethacin on A/J mice were investigated. The non-steroidal antiinflammatory drug (NSAID) indomethacin reduced significantly the number of lung adenomas 3, 4 or 8 months after urethane injection by 28, 30 and 29% respectively. The density of apoptotic cell bodies increased 2.

Do anticoagulation with heparin and protamine reversal alter thrombogenicity of coated and noncoated pulmonary artery catheters?

Objective: To clarify the role of anticoagulation with heparin and protamine reversal on the effectiveness of heparin bonding or coating of pulmonary artery catheters in preventing thrombus formation in the Rhesus monkey.

Design: A controlled, unblinded, open-labeled study.

Setting: A research laboratory at Tulane School of Medicine (New Orleans, LA).

Introducers and protective sleeves may increase thrombogenicity of pulmonary artery catheters.

Objective: To investigate the cause of clot formation on the surface of non-heparin coated/bonded pulmonary artery catheters.

Design: A controlled, unblinded, open-labeled study.

Setting: Research laboratory at Tulane School of Medicine, New Orleans, LA.

Local anesthesia infiltration as a cause of intraoperative tension pneumothorax in a young healthy woman undergoing breast augmentation with general anesthesia.

Pneumothorax may be a medical emergency. Iatrogenic pneumothorax is more common than all other forms of spontaneous pneumothorax, and surgical procedures involving the breast are a frequent setting for this. A 32-year-old, 60 kg, woman without any significant medical history underwent a bilateral breast augmentation and rhinoplasty.