Sulfate Promotes Compact CaCO Formation and Protects Portland Cement from Supercritical CO Attack.

Supercritical (sc) CO in geologic carbon sequestration (GCS) can chemically and mechanically deteriorate wellbore cement, raising concerns for long-term operations. In contrast to the conventional view of "sulfate attack" on cement, we found that adding 0.15 M sulfate to the acidic brine can significantly reduce the impact of scCO attack on Portland cement, resulting in stronger cement than that found in a sulfate-free system.

Madecassoside mitigates acute myocardial infarction injury by activating the PKCB/SPARC signaling pathway.

The current treatments and drugs of myocardial infarction (MI) remain insufficient. In recent years, natural products have garnered significant attention for their potential in treating cardiovascular diseases due to their availability and lower toxicity. Saponins, in particular, showed promising effects for cardiac protection.

A generalist medical language model for disease diagnosis assistance.

The delivery of accurate diagnoses is crucial in healthcare and represents the gateway to appropriate and timely treatment. Although recent large language models (LLMs) have demonstrated impressive capabilities in few-shot or zero-shot learning, their effectiveness in clinical diagnosis remains unproven. Here we present MedFound, a generalist medical language model with 176 billion parameters, pre-trained on a large-scale corpus derived from diverse medical text and real-world clinical records.

Identification of genetic loci and candidate genes underlying Fusarium crown rot resistance in wheat.

A major locus Qfcr.cau-1B conferring resistance to Fusarium crown rot was identified and validated. The putative gene underlying this locus was pinpointed via virus-induced gene silencing.

Plackett-Burman Design Combined with Response Surface Methodology to Recover Polysaccharides with Cardiovascular Protective Potential from Waste Zizania latifolia Bracts.

Zizania latifolia is the second aquatic vegetable in China. The circular valorization of its waste bracts remains ongoing concern. In this work, the cellulase-microwave-assisted extraction (CMAE) of polysaccharides from waste Z.