Publications by authors named "J T Link"
Purpose: To assess the impact of the ratio between photoreceptor (PR) loss and retinal pigment epithelium (RPE) loss on the progression of geographic atrophy (GA) and to explore correlations between abnormal fundus autofluorescence (FAF) patterns and the PR-RPE loss ratio.
Design: Single-centre, retrospective case series.
Methods: Multimodal images from 87 treatment-naïve patients with GA and a follow-up of 6-24 months were included.
Article Synopsis
- * Research examines the responses of U.S. fisheries to these environmental disturbances, revealing negative immediate effects on biomass, landings, and revenue across various regions, especially for ecosystems with more pelagic species and variable shellfish revenue.
- * While some ecosystems showed recovery over time, others, like California's, faced ongoing declines, emphasizing the need for understanding and managing the impacts of extreme events for sustainable marine resource management.
Alveolar and Bone Marrow-derived Macrophages Differ in Metabolism and Glutamine Utilization.
Am J Respir Cell Mol Biol
November 2024
Article Synopsis
- Metabolic activity is crucial for regulating macrophage function, with pro-inflammatory types favoring glycolysis and pro-repair types relying on oxidative processes.
- This study investigates how the metabolism of alveolar macrophages (AM) in mice responds to LPS stimulation, compared to bone marrow-derived macrophages (BMDM).
- Findings show that AM have higher oxygen consumption and fatty acid oxidation; when glutamine metabolism is inhibited, AM alter their metabolic activity and response to LPS differently than BMDM.
Objective: This study aimed to describe the demand for, supply of, and clinic processes associated with behavioral health care delivery in the Military Health System and to examine the clinic-level factors associated with receipt of a minimally adequate dosage of psychotherapy.
Methods: This retrospective study used administrative behavioral health data from eight military treatment facilities (N=25,433 patients; N=241,028 encounters) that were participating in a larger implementation study of evidence-based psychotherapy for posttraumatic stress disorder. Minimally adequate dosage of psychotherapy was defined in two ways: at least three sessions within a 90-day period and at least six sessions within a 90-day period.