Inter- and Intraobserver Repeatability of Myocardial Flow Reserve Values Determined with SPECT Study Using a Discovery NM530c Camera and Corridor 4DM Software.

Background: Myocardial blood flow (MBF) and flow reserve (MFR) examination, especially useful in the diagnosis of multivessel coronary artery disease (CAD), can be assessed with a cadmium-zinc-telluride (CZT) SPECT gamma camera, as an alternative to the expensive and less available PET. However, study processing is not free from subjective factors. Therefore, this paper aims to evaluate intra- and interobserver repeatability of MBF and MFR values obtained by the same operator and two independent operators.

Mask-Related Motion Artifact on 99mTc-MIBI SPECT: Unexpected Pitfalls of SARS-CoV-2 Countermeasures.

A 61-year-old man was referred for myocardial perfusion scintigraphy (MPS) by an occupational physician to exclude coronary artery disease (CAD). The patient had a complete left bundle branch block (LBBB) that rendered the routine exercise stress test non-diagnostic, but otherwise had no history of heart diseases, good stress tolerance with no symptoms of angina, and no abnormalities in transthoracic echocardiogram, apart from contraction patterns typical for LBBB. Initial MPS, performed using technetium-labeled Sestamibi on a Discovery NM 530c camera equipped with solid-state semiconductor detectors, revealed a significant stress-induced ischemia that did not match the good overall condition of the patient.

Assessment of Renal Function Based on Dynamic Scintigraphy Parameters in the Diagnosis of Obstructive Uro/Nephropathy.

This study evaluates the usefulness of parameters allowing assessment of renal function in absolute values in dynamic renal scintigraphy (DRS) with Tc-ethylenedicysteine (Tc-EC) uptake constant (K), mean transit time (MTT), and parenchymal transit time (PTT) in the diagnosis of obstructive uro/nephropathy. The study included 226 people: 20 healthy volunteers, for whom normative values of assessed parameters were determined, and 206 patients. Reproducibility of results obtained by two independent operators, specificity, correlation with estimated GFR (eGFR), and Cohen's kappa were used to evaluate reliability of assessed parameters.

Kidney efficiency index quantitative parameter of a dynamic renal scintigraphy. II. usefulness in the diagnosis of obstructive nephropathy.

Background: One of the main indications for DRS is a diagnosis of obstructive uro-/nephropathy. In standard practice, this study includes the assessment of sequential scintigraphic images, renographic curves and such quantitative parameters as TMAX, T1/2 and split function of each kidney (SF). Due to the relative nature of SF and limitations of diagnostic capabilities of TMAX and T1/2, DRS was expanded to include new quantitative parameters describing kidney function in absolute values.

Kidney Efficiency Index - quantitative parameter of a dynamic renal scintigraphy. I. Theory and preliminary verification.

Background: One of the basic clinical indications for dynamic renal scintigraphy (DRS) is a diagnosis of obstructive uropathy and/or nephropathy. Currently, a basic quantitative criterion for diagnosing nephropathy is the percentage of individual kidney's contribution in the global uptake of a radiopharmaceutical from the blood (so-called Split Function - SF). From a clinical point of view, a parameter evaluating a radiopharmaceutical uptake and reflecting the efficiency of a specific kidney, determined independently of the total uptake of both kidneys, would be much more useful.