United Kingdom dredge disposal returns data, and associated disposal site dataset, for meeting obligations under OSPAR and London Convention/London Protocol.

This paper describes the data that is collected and analysed annually by the Centre for Environment, Fisheries and Aquaculture Science (Cefas), on behalf of the United Kingdom (England, Scotland, Wales, Northern Ireland) and Jersey, Guernsey, and Isle of Man. The respective regulatory authorities provide data on the permits to dispose of dredged material that have been issued in a reporting year (January to December) as well as the amount of material that has been disposed within designated disposal sites within the same reporting year. The data are analysed to determine the contaminant loading that is placed at the respective disposal sites.

A reassessment of TBT action levels for determining the fate of dredged sediments in the United Kingdom.

As part of reviewing the United Kingdom (UK) action levels (ALs) of contaminants for managing the disposal of dredged marine sediment material, tributyl tin (TBT) has been reassessed. TBT is a banned biocide capable of causing severe harm to the marine environment. Its presence is routinely screened for prior to marine disposal of dredged sediment material.

A novel systematic, risk based approach to support the designation of aquatic disposal sites.

Humans rely fundamentally on the marine environment, which is at the same time subject to an increasingly broad range of anthropogenic pressures, leading to growing concerns and the need for effective management for marine protection. One activity is the dredging of ports and harbours which is necessary to maintain safe channels for commercial and recreational navigation. Regulatory authorities in developing countries have few resources to conduct full EIAs for determining dredged material disposal sites but are required to do so under international obligations.

Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC.

Objective: The MHC region harbors the strongest loci for latent autoimmune diabetes in adults (LADA); however, the strength of association is likely attenuated compared with that for childhood-onset type 1 diabetes. In this study, we recapitulate independent effects in the MHC class I region in a population with type 1 diabetes and then determine whether such conditioning in LADA yields potential genetic discriminators between the two subtypes within this region.

Research Design And Methods: Chromosome 6 was imputed using SNP2HLA, with conditional analysis performed in type 1 diabetes case subjects ( = 1,985) and control subjects ( = 2,219).