Is Preoperative Happiness Influencing BREAST-Q Outcomes?

Background: BREAST-Q captures quality of life implications of breast reconstruction but may draw influence from the patients' psychosocial circumstances. This study aims to test: 1) positive affect is associated with higher breast satisfaction and well-being, and 2) socioeconomic status (SES) impacts this relationship.

Methods: This prospective study included breast reconstruction patients from August 2020 to October 2022.

Peripheral Muscle Function and Body Composition in People With Cystic Fibrosis on Elexacaftor/Tezacaftor/Ivacaftor: A Cross-Sectional Single-Centre Study.

Background: People with cystic fibrosis (pwCF) often have multifactorial peripheral muscle abnormalities attributed to, for example, malnutrition, steroid use, altered redox balance and, potentially, CF-specific intrinsic alterations. Malnutrition in CF now includes an increasing prevalence of overweight and obesity, particularly in those receiving CF transmembrane conductance regulator (CFTR) modulator therapy (CFTRm). We aimed to characterise peripheral muscle function and body composition in pwCF on Elexacaftor/Tezacaftor/Ivacaftor (ETI) CFTRm, compared to healthy controls.

Cardiovascular function in people with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor: A cross-sectional, observational, single-centre study.

Background: Cystic fibrosis (CF) has been associated with impaired cardiovascular and endothelial function. CF transmembrane conductance regulator (CFTR) modulator therapy, most recently Elexacaftor/Tezacaftor/Ivacaftor (ETI), has led to improved CFTR function and life expectancy. However, the rising prevalence of obesity in adults is concerning.

Evolution in changing seas: The loss of plasticity under predator invasion and warming oceans.

The impact of invasive predators during the early stages of invasion is often variable in space and time. Such variation is expected to initially favor plasticity in prey defenses, but fixed defenses as invaders become established. Coincident with the range expansion of an invasive predatory crab in the Gulf of Maine, we document rapid changes in shell thickness-a key defense against shell crushing predators-of an intertidal snail.

Effect of condensed heat acclimation on thermophysiological adaptations, hypoxic cross-tolerance, exercise performance, and deacclimation.

Short duration heat acclimation (HA) (≤5 daily heat exposures) elicits incomplete adaptation compared with longer interventions, possibly due to the lower accumulated thermal "dose." It is unknown if matching thermal "dose" over a shorter timescale elicits comparable adaptation to a longer intervention. Using a parallel-groups design, we compared: "condensed" HA (CHA; = 17 males) consisting of 4 × 75 min·day heat exposures [target rectal temperature () 38.