Publications by authors named "J Szer"
Sustainable Infrastructure: Recycled Concrete Aggregates for Cycle Paths.
Materials (Basel)
December 2024
The application of recycled concrete aggregates (RCAs) has become increasingly popular for different types of structures, as presented in several studies. However, depending on the type of structure and the region, RCAs might have different properties. This study aims to investigate the application of RCAs of different origins for substructure layers of the cycle paths located in Central Europe, which was not analysed previously.
View Article and Find Full Text PDFNon-cryopreserved autologous peripheral blood stem cell transplantation for multiple myeloma and lymphoma in countries with limited resources: practice considerations from the Worldwide Network for Blood and Marrow Transplantation.
Mohamed Amine Bekadja Dietger Niederwiser Mohamed A Kharfan-Dabaja Riad El Fakih Laurent Garderet Jeff Szer
Bone Marrow Transplant
January 2025
Article Synopsis
- Autologous peripheral blood stem cell (PBSC) transplantation is a common treatment for conditions like multiple myeloma and lymphomas, and it usually involves freezing the stem cells before transplant.* -
- A recent systematic review of 19 transplant centers that performed non-cryopreserved PBSC transplants showed that the procedure is feasible and safe, with high stem cell viability and low rates of complications.* -
- The study found that stem cell viability was over 90% for multiple myeloma and over 75% for lymphomas, with quick engraftment times, and only 1% transplant-related mortality within 100 days.*
Article Synopsis
- Paroxysmal nocturnal haemoglobinuria (PNH) is a rare blood disorder causing serious issues due to chronic hemolysis and can significantly affect patients' quality of life.
- A post hoc analysis evaluated the effectiveness of pegcetacoplan, a targeted complement C3 inhibitor, in PNH patients with poor bone marrow function from the PEGASUS and PRINCE studies.
- Results showed that while normalisation of certain health parameters was challenging, a significant percentage of patients experienced clinically meaningful improvements in hemoglobin, LDH levels, and fatigue after treatment with pegcetacoplan.