Publications by authors named "J Svehlikova"
Autocorrelation maps for optimal setting in cardiac resynchronization therapy.
Comput Methods Programs Biomed
December 2024
Article Synopsis
- The study focuses on using implanted devices to aid patients with chronic heart failure by analyzing ECG signals, specifically looking at the timing of stimulation/pacing based on QRS duration.
- Researchers evaluated the autocorrelation maps from body surface potential maps of 17 patients, most of whom had left bundle branch block (LBBB), to find differences in heart rhythms compared to healthy controls.
- The results indicate that certain autocorrelation parameters could serve as additional metrics for optimizing cardiac resynchronization therapy (CRT) pacing settings, particularly for patients who respond well to treatment.
Introduction: The inverse problem of electrocardiography describes non-invasively the electrical activity of the heart using potential recordings from tens to hundreds of torso electrodes. Regrettably, the use of numerous electrodes poses a challenge to its integration into routine clinical practice.
Methods: Optimal electrode placements, ranging from 8 to 112 electrodes, were derived from the singular values of the transfer matrices computed for all feasible positions of a single dipole cardiac source across 12 patients with unique geometrical characteristics from the Bratislava dataset.
This study aims to assess the sensitivity of epicardial potential-based electrocardiographic imaging (ECGI) to the removal or interpolation of bad leads.We utilized experimental data from two distinct centers. Langendorff-perfused pig (= 2) and dog (= 2) hearts were suspended in a human torso-shaped tank and paced from the ventricles.
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- The diagnosis of left ventricular hypertrophy (LVH) through ECG primarily relies on measuring the QRS voltage, but this method often lacks sensitivity.
- A new approach emphasizes the understanding of electrical properties of the heart muscle and factors influencing QRS voltage beyond just size, including both spatial and non-spatial determinants.
- This perspective reveals a wide variety of QRS patterns in LVH patients, indicating that a normal QRS complex can still exist despite underlying complications, and highlights the importance of interpreting these changes for assessing cardiovascular risk.
The inverse problem of electrocardiography noninvasively localizes the origin of undesired cardiac activity, such as a premature ventricular contraction (PVC), from potential recordings from multiple torso electrodes. However, the optimal number and placement of electrodes for an accurate solution of the inverse problem remain undetermined. This study presents a two-step inverse solution for a single dipole cardiac source, which investigates the significance of the torso electrodes on a patient-specific level.
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