Publications by authors named "J Suppiah"

Article Synopsis
  • - This study focused on how the dengue virus affects host cell mechanisms and gene expression, highlighting its potential for early prediction and detection of the disease in patients.
  • - Using RNA sequencing, researchers compared the transcriptomes of 16 dengue patients to 10 healthy individuals, identifying thousands of differentially expressed genes (DEGs) associated with various dengue severities.
  • - Key findings included consistent upregulation of certain genes across all dengue patients, providing potential biomarkers for predicting severe dengue, and the involvement of critical biological pathways related to immune response and viral processes.
View Article and Find Full Text PDF

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) may transmit through airborne route particularly when the aerosol particles remain in enclosed spaces with inadequate ventilation. There has been no standard recommended method of determining the virus in air due to limitations in pre-analytical and technical aspects. Furthermore, the presence of low virus loads in air samples could result in false negatives.

View Article and Find Full Text PDF

Objectives: This study aimed to develop susceptible-exposed-infectious-recovered-vaccinated (SEIRV) models to examine the effects of vaccination on coronavirus disease 2019 (COVID-19) case trends in Malaysia during Phase 3 of the National COVID-19 Immunization Program amidst the Delta outbreak.

Methods: SEIRV models were developed and validated using COVID-19 case and vaccination data from the Ministry of Health, Malaysia, from June 21, 2021 to July 21, 2021 to generate forecasts of COVID-19 cases from July 22, 2021 to December 31, 2021. Three scenarios were examined to measure the effects of vaccination on COVID-19 case trends.

View Article and Find Full Text PDF