Publications by authors named "J Stubbs"
Article Synopsis
- - Cervical screening is key for early detection of cervical cancer, but traditional methods face issues like embarrassment and accessibility, making self-collection a viable alternative to increase screening rates among underserved populations.
- - A recent survey of Australian healthcare workers revealed gaps in their understanding of self-collection methods, along with a preference for clinician collection and concerns about patients’ willingness to use self-collection.
- - To improve participation in cervical screening, especially among those who are under- or never-screened, comprehensive education and accessible resources about self-collection are necessary to address knowledge gaps and build patient confidence.
Timely receipt of community-based follow-up after inpatient psychiatric discharge is associated with positive outcomes. This retrospective cross-sectional study aimed to identify socio-demographic and clinical factors associated with failure to receive community mental health follow-up within 7 days. Routinely collected hospital and community mental health data were linked for all inpatients discharged with a mental health condition in 2017 to 2019 in a local health district in New South Wales, Australia.
View Article and Find Full Text PDFOsteopontin (OPN) is a multi-functional glycoprotein that coordinates the innate immune response, prevents nanocrystal formation in renal tubule fluid, and is a biomarker for kidney injury. OPN expression is markedly increased in cystic epithelial cells of polycystic kidney disease (PKD) kidneys; however, its role in PKD progression remains unclear. We investigated the in vitro effects of recombinant OPN on the proliferation of tubular epithelial cells from PKD and normal human kidneys and in vivo effects of OPN deletion on kidney cyst formation, fibrosis, and mineral metabolism in pcy/pcy mice, a non-orthologous model of autosomal-dominant PKD.
View Article and Find Full Text PDFArticle Synopsis
- Research highlights that the accuracy of clinical prognoses for survival after moderate to severe traumatic brain injury (TBI) is crucial since many patients die due to withdrawal of life-sustaining therapy based on assumed poor outcomes.
- The study's objective was to evaluate if the automated measurement of cerebral contusion size and location can enhance the IMPACT score, a current prognostic model that doesn’t account for where brain injuries occur.
- Conducted in 18 US trauma centers, the study assessed adult patients with moderate or severe TBI using an AI tool, BLAST-CT, to analyze CT scans, focusing on how contusion characteristics relate to long-term recovery outcomes using tools like the Glasgow Outcome Scale.
Biotic interactions, such as plant-animal seed dispersal mutualisms, are essential for ecosystem function. Such interactions are threatened by the possible extinction of the animal partners. Using a data set that includes plant-lemur interactions across Madagascar, we studied the current state of knowledge of these interactions and their structure to determine which plant species are most at risk of losing dispersal services due to the loss of lemurs.
View Article and Find Full Text PDF