Publications by authors named "J Stranne"

Trials have shown that prostate-specific membrane antigen (PSMA)-based positron emission tomography/computed tomography (PET/CT) is more accurate than conventional imaging for staging of nodal status in prostate cancer. We discuss the advantages of PSMA PET/CT over current options for nodal staging and highlight the issues that need to be resolved for implementation of this modality in routine practice.

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Article Synopsis
  • The IPA trial is a prospective, multicenter study aimed at understanding the factors that contribute to urinary incontinence after robot-assisted laparoscopic radical prostatectomy (RALP) in patients.
  • It involves detailed evaluations using various imaging and urodynamic tests both before and three months after surgery, with incontinence data collected through patient questionnaires.
  • As of October 2023, the trial has included 207 out of a planned 1,000 patients, and the findings aim to enhance knowledge of post-RALP incontinence to inform better treatment decisions for prostate cancer patients.
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A phytoestrogen-rich diet has been suggested to reduce tumor proliferation among men with prostate cancer, and the effect may differ between men with different polymorphisms of the estrogen receptor-beta gene (ERβ). Patients with low- or intermediate-risk prostate cancer scheduled for radical prostatectomy were randomized to an intervention group ( = 71) provided with soybeans and flaxseeds (∼200 mg phytoestrogens/day) to eat until surgery (approximately 6 wk) or to a control group ( = 69). Tumor proliferation was assessed using Ki-67 indexes, prostate-specific antigen (PSA) concentrations were analyzed in blood, and ERβ polymorphism was genotyped in all subjects.

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