Publications by authors named "J Strancar"

Article Synopsis
  • Listeria monocytogenes can form tough biofilms in food processing areas, making it hard to eliminate despite existing control strategies.
  • Research on fungal proteins showed that they effectively disrupt biofilm formation without directly killing the bacteria at higher temperatures.
  • Fungal lectins specifically inhibited biofilm development at room temperature, suggesting potential use in preventing Listeria contamination on surfaces in food processing.
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In the United States, Black individuals have higher rates of cancer mortality than any other racial group. Here, we examine chromosome copy number changes in cancers from more than 1800 self-reported Black patients. We find that tumors from self-reported Black patients are significantly more likely to exhibit whole-genome duplications (WGDs), a genomic event that enhances metastasis and aggressive disease, compared to tumors from self-reported white patients.

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Article Synopsis
  • Air pollution is linked to higher risks of neurodegenerative diseases like Alzheimer's and Parkinson's, which affect memory and cognitive functions.
  • Traditional models of sporadic Alzheimer's fail to capture all disease features, highlighting the need for new models driven by environmental factors.
  • Research using live-cell imaging in SH-SY5Y cells shows that exposure to certain pollutants, like iron oxide and diesel particles, leads to neurodegenerative symptoms, while engineered cerium oxide nanoparticles do not have the same damaging effects.
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Unlabelled: Nanoparticle toxicity assessments have moved closer to physiological conditions while trying to avoid the use of animal models. An example of new in vitro exposure techniques developed is the exposure of cultured cells at the air-liquid interface (ALI), particularly in the case of respiratory airways. While the commercially available VITROCELL Cloud System has been applied for the delivery of aerosolized substances to adherent cells under ALI conditions, it has not yet been tested on lung surfactant and semi-adherent cells such as alveolar macrophages, which are playing a pivotal role in the nanoparticle-induced immune response.

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Knowing the temperature distribution within the conducting walls of various multilayer-type materials is crucial for a better understanding of heat-transfer processes. This applies to many engineering fields, good examples being photovoltaics and microelectronics. In this work we present a novel fluorescence technique that makes possible the non-invasive imaging of local temperature distributions within a transparent, temperature-sensitive, co-doped Er:GPF1Yb0.

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