Artificial Intelligence-Based Tool for Tumor Detection and Quantitative Tissue Analysis in Colorectal Specimens.

Digital pathology adoption allows for applying computational algorithms to routine pathology tasks. Our study aimed to develop a clinical-grade artificial intelligence (AI) tool for precise multiclass tissue segmentation in colorectal specimens (resections and biopsies) and clinically validate the tool for tumor detection in biopsy specimens. The training data set included 241 precisely manually annotated whole-slide images (WSIs) from multiple institutions.

Osseous Thoracic Foraminal Stenosis with Unilateral Congenital Absence of T1 Rib A Case Report.

A 43-year-old male with a congenital absence of his left T1 rib developed a left-sided T1-T2 spinal facet joint arthrosis and stenosis and clinical signs and symptoms of T1 radiculopathy. The patient was treated with a decompressive laminotomy and partial medial facetectomy resulting in immediate resolution of symptoms. This report should alert clinicians to consider this potential etiology when evaluating patients with thoracic radiculopathy.

Biologics and Minimally Invasive Approach to TLIFs: What Is the Risk of Radiculitis?

Background: Bone morphogenetic protein (BMP) and allograft containing mesenchymal stem cells (live cell) are popular biologic substitutes for iliac crest autograft used in transforaminal lumbar interbody fusion (TLIF). Use of these agents in the pathogenesis of postoperative radiculitis remains controversial. Recent studies have independently linked minimally invasive (MIS) TLIF with increased radiculitis risk compared to open TLIF.

MRI Radiological Predictors of Requiring Microscopic Lumbar Discectomy After Lumbar Disc Herniation.

Study Design: Retrospective cohort study.

Objective: To investigate radiological differences in lumbar disc herniations (herniated nucleus pulposus [HNP]) between patients receiving microscopic lumbar discectomy (MLD) and nonoperative patients.

Methods: Patients with primary treatment for an HNP at a single academic institution between November 2012 to March 2017 were divided into MLD and nonoperative treatment groups.

Preoperative MRI predictors of health-related quality of life improvement after microscopic lumbar discectomy.

Background: Lumbar herniated nucleus pulposus (HNP) is a common spinal pathology often treated by microscopic lumbar discectomy (MLD), though prior reports have not demonstrated which preoperative MRI factors may contribute to significant clinical improvement after MLD.

Purpose: To analyze the MRI characteristics in patients with HNP that predict meaningful clinical improvement in health-related quality of life scores (HRQoL) after MLD.

Study Design/setting: Retrospective clinical and radiological study of patients undergoing MLD for HNP at a single institution over a 2-year period.