High toxinogenic potential of from wild ungulates in Brandenburg, Germany with a low level of antibiotic resistance.

Introduction: Data regarding the occurrence and virulence of (.) in wild living animals is rare. However, may carry a multitude of virulence factors and express resistance to several antimicrobial substances.

Survey on colostrum management by German dairy farmers focusing on frozen colostrum storage.

Because calves are born with low levels of antibodies, effective colostrum management is one of the most critical factors for successful calf rearing. A timely and adequate supply of sufficiently high-quality colostrum immediately after birth is essential to ensure the passive immunization of calves. Frozen colostrum reserves are recommended to fulfill the immunological and nutrient requirements of newborn calves, even in exceptional situations; however, the implementation rates on German dairy farms and challenges of realization remain unclear.

Effect of Climatic Condition, Type of Trough and Water Cleanliness on Drinking Behavior in Dairy Cows.

Increasing ambient temperatures lead to higher water intake and higher risks of microbial growth in cattle troughs. This study aims to analyze drinking water quality and dairy cows' drinking behavior ( = 8081 drinking episodes) on a commercial farm with 135 and 144 lactating cows in two climatic conditions, considering trough type and cleanliness, respectively. Daily video recording was conducted at two trough types (two open troughs, 70 L; two-valve troughs, variable volume of 5-15 L) in the first two hours after feeding ( = 60 days in total) under cold (December 2019-February 2020) and warm ambient temperatures (September 2021).

Translation Fidelity and Respiration Deficits in CLPP-Deficient Tissues: Mechanistic Insights from Mitochondrial Complexome Profiling.

The mitochondrial matrix peptidase CLPP is crucial during cell stress. Its loss causes Perrault syndrome type 3 (PRLTS3) with infertility, neurodegeneration, and a growth deficit. Its target proteins are disaggregated by CLPX, which also regulates heme biosynthesis via unfolding ALAS enzymes, providing access for pyridoxal-5'-phosphate (PLP).