Visceral fat has been identified as a key contributor to metabolic disorders owing to its association with decreased adipocytokine function. Perivascular adipose tissue (PVAT), a specialized local deposit of adipose tissue surrounding arteries, has been shown to regulate vascular tone through adipocytokine functions but is compromised in obesity, contributing to increased vascular resistance. This study aimed to investigate the correlation between PVAT of the superior mesenteric artery (SMA), visceral adipose tissue (VAT), body mass index (BMI), and waist-to-hip ratio (WHR).
View Article and Find Full Text PDFEpidemic models study the spread of undesired agents through populations, be it infectious diseases through a country, misinformation in social media or pests infesting a region. In combating these epidemics, we rely neither on global top-down interventions, nor solely on individual adaptations. Instead, interventions commonly come from local institutions such as public health departments, moderation teams on social media platforms or other forms of group governance.
View Article and Find Full Text PDFBackground: There is increased awareness about the need for quality improvement (QI) education for trainees within clinical training programs. However, formal integration of a QI curriculum into graduate medical education (GME) remains a work-in-progress. We describe the creation and implementation of a novel, virtual QI curriculum complemented by virtual-based workshops.
View Article and Find Full Text PDFBackground: Congenital mirror movements (CMM) is a rare neurodevelopmental disorder characterized by involuntary movements from one side of the body that mirror voluntary movements on the opposite side. To date, five genes have been associated with CMM, namely DCC, RAD51, NTN1, ARHGEF7, and DNAL4.
Objective: The aim of this study is to characterize the genetic landscape of CMM in a large group of 80 affected individuals.