Enhanced agglutination reaction of ABO subgroups by gold nanoparticle solution: implication for identification of ABO subgroups.

Although the ABO blood group is the most significant in blood group system in human, other subgroups system is also important to be concerned in blood banking laboratory. ABO subgroups have weak antigen potency on red blood cell. In some cases, they could not been detected by cell grouping and serum grouping methods.