Publications by authors named "J Srigley"

Purpose: Over the past 50 years, multiple pathology organizations worldwide have evolved in cancer histopathology reporting from subjective, narrative assessments to structured, synoptic formats using controlled vocabulary. These reporting protocols include the required data elements that represent the minimum set of evidence-based, clinically actionable parameters necessary to convey the diagnostic, prognostic, and predictive information essential for patient care. Despite these advances, the synoptic reporting protocols were not harmonized across the various pathology organizations.

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  • Evidence-based bundles for inserting and maintaining central lines significantly lower the rates of CLABSI in ICUs.
  • Researchers examined how well these prevention programs were adopted and followed in ICUs across a large network of Canadian hospitals.
  • The study focused on the relationship between compliance with these bundles and actual CLABSI rates.
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Background: The COVID-19 pandemic highlighted that hand hygiene (HH) is key in preventing health care-associated infections. Patients and families are understudied targets for infection prevention and control practices. Previous campaigns to change HH behavior have been effective, but often face systemic challenges with implementation.

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  • * 81% of the 5,143 pediatric cases occurred during the Omicron period, with fewer children needing intensive care compared to pre-Omicron times (11% vs. 14%), but no notable difference in mortality rates was found.
  • * The findings emphasize that many hospitalized children had pre-existing health conditions and indicate a surge in healthcare-associated COVID-19 cases during Omicron, although overall disease severity appeared to decline.
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  • - Oncocytic renal neoplasms pose significant diagnostic challenges, yet are generally nonaggressive, prompting discussion about the necessity of differentiating emerging subtypes like eosinophilic solid and cystic renal cell carcinoma and others.
  • - A survey of 63 urologic pathologists revealed that many encounter complex oncocytic tumors frequently, with 70% agreeing that eosinophilic solid and cystic renal cell carcinoma should be recognized as a distinct category, while opinions were more divided on other types.
  • - Diagnostic approaches varied among pathologists, with 60% hesitant to diagnose oncocytoma through needle biopsies, and a near split on the routine use of immunohistochemistry; common genetic testing was
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