Ascertaining the Environmental Advantages of Pavement Designs Incorporating Recycled Content through a Parametric and Probabilistic Approach.

Reclaimed asphalt pavement (RAP) is a widely used end-of-life (EoL) material in asphalt pavements to increase the material circularity. However, the performance loss due to using RAP in the asphalt binder layer often requires a thicker layer, leading to additional material usage, energy consumption, and transportation effort. In this study, we developed a parametric and probabilistic life cycle assessment (LCA) framework to robustly compare various pavement designs incorporating recycled materials.

Validation of the brief physical activity assessment tool: Comparison of telephone and in-person administration.

We examined the reliability and validity of the Brief Physical Activity Assessment Tool (BPAAT) when administered by telephone interview compared to in-person administration. We analyzed data from the Epi-asthma study. Adult participants registered in the participating Portuguese primary health care centres (PCC) completed the BPAAT via telephone.

PM/PM ratios in southernmost Brazilian cities and its relation with economic contexts and meteorological factors.

The PM/PM ratio is a metric used to distinguish the primary sources of particulate matter (PM) within a given environment. Higher ratios often indicate significant contributions from anthropogenic sources, while smaller ratios suggest a substantial influence from natural origins. However, various contextual factors can influence this ratio.

Three-Dimensional Printing/Bioprinting and Cellular Therapies for Regenerative Medicine: Current Advances.

The application of three-dimensional (3D) printing/bioprinting technologies and cell therapies has garnered significant attention due to their potential in the field of regenerative medicine. This paper aims to provide a comprehensive overview of 3D printing/bioprinting technology and cell therapies, highlighting their results in diverse medical applications, while also discussing the capabilities and limitations of their combined use. The synergistic combination of 3D printing and cellular therapies has been recognised as a promising and innovative approach, and it is expected that these technologies will progressively assume a crucial role in the treatment of various diseases and conditions in the foreseeable future.

Hepatic Estrogen Receptor Alpha Overexpression Protects Against Hepatic Insulin Resistance and MASLD.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with cardiometabolic risk. Although studies have shown that estradiol positively contributes to energy metabolism via estrogen receptor alpha (ERα), its role specifically in the liver is not defined. Therefore, this study aimed to evaluate the effects of ERα overexpression, specifically in the liver in mice fed a high-fat diet (HFD).