Publications by authors named "J Sophonphan"
Background: Rates of carbapenem-resistant Acinetobacter baumannii are rising in Thailand. Although high-dose (HD) sulbactam is recommended for treating carbapenem-resistant A. baumannii infections, data on plasma sulbactam concentrations in children are limited.
View Article and Find Full Text PDFBackground And Aims: The long-term respiratory sequelae of COVID-19 infection in children remain poorly understood and may differ across countries. This study aims to investigate the respiratory sequelae, including residual respiratory symptoms and pulmonary function in Thai children. The secondary aim is to identify factors associated with the respiratory sequelae.
View Article and Find Full Text PDFPrevalence and Risk Factors of Healthcare-Associated Infections among Hospitalized Pediatric Patients: Point Prevalence Survey in Thailand 2021.
Children (Basel)
June 2024
Article Synopsis
- Healthcare-associated infections (HAIs) in hospitalized pediatric patients were studied, revealing a prevalence of 3.9% across various age groups in 41 hospitals in Thailand from March to May 2021.
- * Significant risk factors for HAIs included longer hospital stays and the use of central venous catheters, with the highest odds of infection noted in patients with prolonged stays and LRTIs being the most common type of HAI.
- * The findings underscore the need for strategies to reduce hospital length of stay and improve infection control practices, emphasizing ongoing surveillance of HAIs in pediatric care settings.
ChulaCov19 mRNA vaccine demonstrated promising phase 1 results. Healthy adults aged 18-59 years were double-blind randomised 4:1 to receive two intramuscular doses of ChulaCov19 50 µg or placebo. Primary endpoints were safety and microneutralization antibody against-wild-type (Micro-VNT50) at day 50.
View Article and Find Full Text PDFA multivariable normal tissue complication probability model for predicting radiation-induced hypothyroidism in nasopharyngeal carcinoma patients in the modern radiotherapy era.
J Radiat Res
January 2024
Radiation-induced hypothyroidism (RHT) is a common long-term complication for nasopharyngeal carcinoma (NPC) survivors. A model using clinical and dosimetric factors for predicting risk of RHT could suggest a proper dose-volume parameters for the treatment planning in an individual level. We aim to develop a multivariable normal tissue complication probability (NTCP) model for RHT in NPC patients after intensity-modulated radiotherapy or volumetric modulated arc therapy.
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