Persistence of humoral immunity to tetanus and diphtheria in hematopoietic stem cell transplant recipients after post-transplant immunization.

Background: Persistence of humoral immunity was evaluated in 82 hematopoietic stem cell transplant recipients up to 12.5 years after post-transplant immunization against tetanus and diphtheria.

Procedure: New immunization, initiated at least 12 months after transplantation, consisted of an average three-dose schedule of vaccine administration on day 1, month 3, and month 12.

[What did the campaigns against childhood vaccination accomplish in developed countries?].

An overview is given on the literature on the campaigns against vaccination of children. Such campaigns were organized in the developed countries of the Western Europe and they have occurred recently also in the Czech Republic. From these actions and namely from the consequence of the limited vaccination it is possible to get an important lesson and to use them as arguments for our own vaccination program.

[Post-vaccination immunity after allogenic and autologous bone marrow transplantation].

In the submitted review the author describes time correlation's of reconstitution of immunity during the post-transplantation period in patients after autologous and allogeneic bone marrow transplantations. The authors presents values of different immunological parameters incl. functional examinations of immunity by the method of blastic lymphocyte transformation after stimulation with mitogens and vaccination antigens during the post-transplantation period.

[Vaccination in children with neurologic diseases].

The authors explain the main risks of immunization of children with affections of the central nervous system. For practical reasons the diseases are divided into four groups: 1. Perinatal affections and developmental diseases of the CNS.

[Neurologic disorders after vaccination against measles and mumps].

The authors analyse neurological disorders which developed after immunization with vaccines against measles (Movivac) and after immunization against measles and mumps (Mopavac) in 60 children. The majority of reactions developed at the time of the side-reaction after immunization and was manifested by febrile attacks.