Breakthrough instruments and products: Lattice Lightsheet 7-Non-invasive imaging of the subcellular dynamics of life.

Light sheet fluorescence microscopy has become an established method for fast and sensitive imaging of living specimens with minimum phototoxicity and photobleaching. By adding lattice structures to the light sheet, the ZEISS Lattice Lightsheet 7 makes this technique available for live cell imaging at subcellular resolution while also allowing microscopists to use their standard sample carriers.

The Use of Intraoperative Digital Radiography Alignment Software to Assess Implant Placement in Total Hip Arthroplasty.

Purpose Of Review: Total hip arthroplasty (THA) is a highly successful surgery with growing rates of utilization in the USA, but surgical outliers leading to postoperative complications remain a concern. There is need for a standard system of accurate, predictable intraoperative evaluation to decrease component positioning outliers. Many current intraoperative imaging systems have shown promise, but there are drawbacks that have led to slow adoption.

Crystalline Pr:SrAl12O19 waveguide laser in the visible spectral region.

We fabricated waveguides in Pr:SrAl(12)O(19) crystals by direct femtosecond laser writing. The propagation losses were calculated to be as low as 0.16 dB/cm at a wavelength of 633 nm.

Highly efficient Yb:YAG channel waveguide laser written with a femtosecond-laser.

Using a femtosecond Ti:Sapphire laser, micro-tracks of material damage were written into Yb:YAG crystals. Waveguiding was achieved in a channel between pairs of tracks with guiding losses of 1.3 dB/cm at a wavelength of 1063 nm, due to a stress induced change of the refractive index.