Publications by authors named "J Shahraki"
Correction: Hesperidin neuroprotective effects against carbon monoxide-induced toxicity in male rats.
Naunyn Schmiedebergs Arch Pharmacol
October 2024
Objective: The present study examined effects of resistance training (RT) and resveratrol (RES) alone and together on acrylamide (AC)-induced memory impairment in rats.
Materials And Methods: Animals were divided into 6 groups: (1) Control group which received normal saline intraperitoneally (ip) daily for 8 weeks; (2) Scopolamine (SCO) group which received SCO (1 mg/kg/day, ip) for 8 weeks; (3) AC group which received AC (5 mg/kg/day, ip) for 8 weeks; (4) AC + RT group which received AC (5 mg/kg/day, ip) for 8 weeks and performed RT (5 days a week for 8 weeks); (5) AC + RES group which received AC (5 mg/kg/day, ip) and RES (1 mg/kg/day, ip) for 8 weeks; and (6) AC + RT + RES group which received AC (5 mg/kg/day, ip) and RES (1 mg/kg/day, ip) for 8 weeks and performed RT (5 days a week for 8 weeks). On day 53, animal training began in the Morris Water Maze (MWM) and 24 hr after the last training, the probe test was performed.
Hesperidin neuroprotective effects against carbon monoxide-induced toxicity in male rats.
Naunyn Schmiedebergs Arch Pharmacol
October 2024
Carbon monoxide (CO) is produced via incomplete combustion of fossil fuels and it may cause long-term neurological sequel upon exposure. Hesperidin (HES), a flavanone glycoside found in citrus plants, exerts diverse beneficial health effects. The present study mechanistically examined the neuroprotective effects of HES in CO-poisoned rats.
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- Arsenic poisoning is a significant global health issue known to cause various serious health problems, including cancer and liver damage, leading researchers to explore protective effects of curcumin.
- In experiments using isolated rat liver cells, curcumin was applied in different concentrations before arsenic exposure to determine its protective properties against cell damage.
- Results indicated that low doses of curcumin (2 µM) effectively reduced oxidative stress and cell damage caused by arsenic, while higher doses did not show similar protective effects and may even worsen the situation.
Objective: Gallic acid (GA) is an organic acid that possesses anti-inflammatory effects as it inhibits the production of metalloproteinases, tissue plasminogen activator, growth factors and adhesion molecules. Since formation of abdominal surgery-induced adhesion bands is accompanied by inflammation, angiogenesis and cell proliferation, in the current study, we assessed potential beneficial properties of GA against adhesion bands formation in rats.
Materials And Methods: Thirty-six adult male rats were assigned into six groups of six animals.