Publications by authors named "J Seuntjens"
Article Synopsis
- The radiation therapy field is rapidly developing AI models, but there is a lack of adoption in clinical practice due to unclear guidelines on their development and validation.
- A Delphi process was used to create a comprehensive guideline, involving discussions among authors to identify key topics like decision making, image analysis, and ethics related to AI in radiation therapy.
- The resulting guideline includes 19 highly recommended statements aimed at improving the development and reporting of AI tools, ultimately facilitating their integration into clinical workflows.
Background: The conventional theories and methods of determining the ion recombination correction factor, such as Boag theory and the related two voltage method and Jaffé plot extrapolation, do not seem to yield accurate results in FLASH /high dose per pulse (DPP) beams ( 10 mGy DPP). This is due to the presence of a large free electron fraction that distorts the electric field inside the chamber sensitive volume. To understand the influence of these effects on the ion recombination correction factor and to develop new expressions for it, it is necessary to re-visit the underlying physics.
View Article and Find Full Text PDFPurpose: This work aims at reviewing challenges and pitfalls in proton facility design related to equipment upgrade or replacement. Proton therapy was initially developed at research institutions in the 1950s which ushered in the use of hospital-based machines in 1990s. We are approaching an era where older commercial machines are reaching the end of their life and require replacement.
View Article and Find Full Text PDFBackground: Mixed photon-electron beam radiotherapy (MBRT) is a technique that combines the use of both photons and electrons in one single treatment plan to exploit their advantageous and complimentary characteristics. Compared to other photon treatment modalities, it has been shown that the MBRT technique contributes to better target coverage and organ-at-risk (OAR) sparing. However, the use of combined photons and electrons in one delivery makes the technique more complex and a well-established quality assurance (QA) protocol for MBRT is essential.
View Article and Find Full Text PDFBackground: Mixed electron-photon beam radiation therapy (MBRT) is an emerging technique in which external electron and photon beams are simultaneously optimized into a single treatment plan. MBRT exploits the steep dose falloff and high surface dose of electrons while maintaining target conformity by leveraging the sharp penumbra of photons.
Purpose: This study investigates the dosimetric benefits of MBRT for soft tissue sarcoma (STS) patients.