Publications by authors named "J Seni"

Article Synopsis
  • The study focused on understanding the distribution of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-Ec) in patients and their hospital environment to improve infection prevention strategies.
  • Researchers collected rectal swabs from patients and swabs from the hospital environment, identifying 209 ESBL isolates, with 15 being ESBL-Ec originating from both patients (53.3%) and the environment (46.7%).
  • The findings revealed diverse strains of ESBL-Ec with multiple drug resistance genes and plasmids, indicating a need for routine screening upon patient admission to prevent infections.
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Article Synopsis
  • * The study examined 1,093 pregnant women at Bugando Medical Center, finding that factors like anemia and prior antenatal care are linked to higher ASB risk.
  • * Women with ASB showed significantly higher rates of pre-term labor, premature rupture of membranes, and low birth weight, with E. coli being the most frequent bacteria identified.
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Background: Bacterial pneumonia is among the leading causes of morbidity and mortality worldwide. The extensive misuse and overuse of antibiotics observed during the Corona Virus Disease 2019 (COVID-19) pandemic may have changed the patterns of pathogens causing bacterial pneumonia and their antibiotic susceptibility profiles. This study was designed to establish the prevalence of culture-confirmed bacterial pneumonia and describe their antimicrobial susceptibility profile in adult patients who presented with signs and symptoms of lower respiratory tract infections (LRTIs) during the COVID-19 pandemic.

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Objectives: To delineate the epidemiology and antimicrobial resistance (AMR) trends of pathogens causing urinary tract infections (UTIs) during (June 2019-June 2020) and after (March-July 2023) the implementation of the National Action Plan on AMR 2017-2022 in Mwanza, Tanzania.

Methods: This cross-sectional study was conducted among 2097 patients with clinical symptoms of UTIs during (n = 1144) and after (n = 953) the National Action Plan on AMR 2017-2022. Quantitative urine culture was done to isolate significant bacteria causing UTI, which were then identified to the species level and tested for antimicrobial susceptibility.

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Objective: Understanding microbiota colonizing ocular surfaces is key to expedite antibiotic prophylactic options for ocular surgeries, and therefore, prevent subsequent surgical site infections (SSIs). To fill this critical gap, we aimed at determining the prevalence and antibiotic susceptibility patterns of bacteria colonizing the external ocular surfaces of 224 patients undergoing ocular surgeries at Bugando Medical Centre (BMC) in Mwanza, Tanzania between May and August 2023.

Results: The study participants had a median age of 62.

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