Integrated Metabolomic, Molecular Networking, and Genome Mining Analyses Uncover Novel Angucyclines From sp. RO-S4 Strain Isolated From Bejaia Bay, Algeria.

Multi-omic approaches have recently made big strides toward the effective exploration of microorganisms, accelerating the discovery of new bioactive compounds. We combined metabolomic, molecular networking, and genomic-based approaches to investigate the metabolic potential of the sp. RO-S4 strain isolated from the polluted waters of Bejaia Bay in Algeria.

Dorsal locking plates versus staples in four-corner fusion: a comparative clinical and radiological study.

Introduction: Four-corner fusion was described in 1984 by HK Watson for the treatment of SLAC wrist. This intervention has undergone few changes since that description, but the debate on the fixation method is still not resolved.

Hypothesis: Dorsal locking plates provide better stability, short immobilization and a quicker return to daily activities than traditional fixation methods such as staples.

The role of three-ligament tenodesis in the treatment of chronic scapholunate instability.

Restoring ligamentous control in dissociative carpal instability is a major issue in protecting against osteoarthritis. We present clinical and radiological results for 20 patients who underwent flexor carpi radialis three-ligament tenodesis and were prospectively reviewed at a mean follow-up of 25.1 months.

Chronic scapholunate instability treated by scaphocapitate fusion: a midterm outcome perspective.

Introduction: Chronic scapholunate instability can lead to functional deficits and radiocarpal osteoarthritis. A number of procedures, namely scapho-trapezio-trapezoid (STT) fusion, scaphocapitate (SC) fusion or soft tissue reconstruction procedures, aim to improve function while protecting the wrist from osteoarthritis.

Hypothesis: Define the role of scaphocapitate fusion in comparison to STT fusion and capsulodesis and ligament reconstruction.

[Primary ray resection as an alternative to microsurgical replantation in the management of ring finger avulsion].

Objectives: Ray resection of the metacarpal with conservation of the proximal end is a technique of management of complete ring avulsion injuries in the emergency situation. This study is a functional evaluation of the technique in comparison to replantation.

Methods: The present series includes 11 patients, average age of 35 years, predominantly manual workers, operated between October 2005 and July 2007.