Publications by authors named "J Scullion"
Does methylene blue improve outcomes in patients with post-cardiac surgery vasoplegic syndrome?
Interdiscip Cardiovasc Thorac Surg
December 2024
Objectives: A best evidence topic was written according to a structured protocol described in ICVTS. The question addressed was: "In patients with vasoplegic syndrome after cardiopulmonary bypass (CPB), does adjunctive methylene blue improve outcomes including reduced mortality, morbidity and vasopressor requirements?"
Methods: Ovid Medline was searched using a reported search algorithm. Articles that represented the best evidence to answer the clinical question were selected, tabulated and discussed.
Article Synopsis
- Grasslands can help manage water and reduce flood risks through specific plants that improve soil and support earthworms.
- Two experiments tested different forage plants like red clover and chicory to see how well they let water soak into the ground over time.
- Red clover and white clover were found to be best at helping water infiltration, with red clover having thicker roots and white clover supporting more earthworms.
Discharge bundles, comprising evidence-based practices to be implemented prior to discharge, aim to optimise patient outcomes. They have been recommended to address high readmission rates in patients who have been hospitalised for an exacerbation of chronic obstructive pulmonary disease (COPD). Hospital readmission is associated with increased morbidity and healthcare resource utilisation, contributing substantially to the economic burden of COPD.
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- Agriculture impacts flooding differently based on land elevation, with low lands focusing on soil compaction and uplands on afforestation, while the issue of soil acidification from inadequate liming is often ignored.
- In Wales, nearly 20% of upland grasslands are at risk of acidification, particularly on steep slopes where reduced water infiltration may lead to increased runoff and flood risk.
- Research shows that acidic soils have significantly lower infiltration rates and fewer earthworms, which are crucial for water retention; therefore, understanding soil health is vital for flood risk modeling.
Introduction: A multi-site randomized controlled trial was carried out between 2015 and 2019 to evaluate the impacts on quality of life of an intradialytic exercise programme for people living with chronic kidney disease. This included a qualitative process evaluation which gave valuable insights in relation to feasibility of the trial and of the intervention in the long-term. These can inform future clinical Trial design and evaluation studies.
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