Publications by authors named "J Scot Estep"
Background: Effective and timely decongestion in acute heart failure (AHF) coupled with careful discharge planning is critical in the successful treatment of patients hospitalized for AHF. We leveraged an implementation science framework to develop a health system-wide diuretic management protocol (DMP) based on emerging clinical evidence.
Methods: We conducted stakeholder interviews using the Integrated Promoting Action on Research Implementation in Health Services (iPARiHS) Framework.
Background: Association of genetic factors with non-invasive tests (NITs) for MASLD has not been well established.
Methods: Clinical and laboratory data, liver biopsy and/or liver stiffness measurement (LSM) by transient elastography were collected from MASLD patients seen in tertiary care hepatology practices. Minor allele frequency for genomic loci rs641738 (MBOAT7), rs58542926 (TM6SF2), rs738409 (PNPLA3), rs62305723 (HSD1713B) were evaluated for association with high ELF (≥11.
Article Synopsis
- In patients with heart failure-related cardiogenic shock due to cardiac amyloidosis, using an intra-aortic balloon pump (IABP) may enhance hemodynamic stability and support their transition to advanced therapies like heart transplants.
- A study reviewed 23 patients with cardiac amyloid who received IABP and found a 1-year survival rate of 74%, with 65% of them progressing to heart transplants.
- The use of IABP notably increased mean arterial pressure and cardiac indices while decreasing various pressures related to heart function, indicating significant improvement in their cardiovascular status.
Article Synopsis
- Heart failure (HF) is a growing health issue with increasing prevalence and mortality, requiring effective treatment strategies.
- Current foundational therapies for HF include a mix of medications (like ARNIs and SGLTis) and device-based interventions (like ICDs and CRT), though significant risks remain even with treatment.
- The focus is on enhancing care for HF patients through early diagnosis, personalized treatment plans, and continued research into optimizing the use of emerging device therapies alongside existing pharmacological options.