Publications by authors named "J Schier"
Meiotic spindles are critical to ensure chromosome segregation during gamete formation. Oocytes lack centrosomes and use alternative microtubule-nucleation mechanisms for spindle building. How these mechanisms are regulated is still unknown.
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- * Effective survival depends on quick cardiopulmonary resuscitation and the use of external defibrillators for patients with shockable rhythms, but current response systems still show unsatisfactory outcomes.
- * Recent studies, particularly the TTM2 trial, suggest that targeting lower body temperatures (33 °C) for post-resuscitation care does not improve neurological outcomes compared to maintaining normal body temperature (36 °C to 37.5 °C), indicating a need to revise current temperature management guidelines.
Lateral roots (LR) are essential components of the plant edaphic interface; contributing to water and nutrient uptake, biotic and abiotic interactions, stress survival, and plant anchorage. We have identified the TETRATRICOPEPTIDE-REPEAT THIOREDOXIN-LIKE 3 (TTL3) gene as being related to LR emergence and later development. Loss of function of TTL3 leads to a reduced number of emerged LR due to delayed development of lateral root primordia (LRP).
View Article and Find Full Text PDFTelemedical cardiac risk assessment by implantable cardiac monitors in patients after myocardial infarction with autonomic dysfunction (SMART-MI-DZHK9): a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial.
Lancet Digit Health
February 2022
Background: Cardiac autonomic dysfunction after myocardial infarction identifies patients at high risk despite only moderately reduced left ventricular ejection fraction. We aimed to show that telemedical monitoring with implantable cardiac monitors in these patients can improve early detection of subclinical but prognostically relevant arrhythmic events.
Methods: We did a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial at 33 centres in Germany and Austria.