Publications by authors named "J Scheiman"
Background: The complex relationship among sleep, exercise, and the gut microbiome presents a unique opportunity to improve health and wellness. Here, we conducted the first large-scale investigation into the influence of a novel elite athlete-derived probiotic, consisting of a multi-strain Lactobacillus consortium, on sleep quality, exercise recovery, and gut microbiome composition in both elite athletes (n = 11) and the general population (n = 257).
Results: Our two-phase study design, which included an open-label study followed by a controlled longitudinal study in a professional soccer team, allowed us to identify key interactions between probiotics, the gut microbiome, and the host.
Article Synopsis
- The study aimed to create and test a report card for endoscopic retrograde cholangiopancreatography (ERCP) to improve audit and feedback, which is less researched compared to tools for procedures like colonoscopy.
- The report card incorporated various indicators for assessing technical performance, adverse events, and patient experiences, with positive feedback from ERCP specialists on its content but concerns over the practicality of gathering detailed data for evaluation.
- Despite challenges in data acquisition, the developed report card shows promise as a useful audit tool, especially with future advancements in video recording and AI technology aiding its implementation in clinical settings.
Article Synopsis
- Difficult biliary cannulation (DBC) significantly raises the risk of post-ERCP pancreatitis (PEP), especially when combined with high pre-procedure risk factors.
- In a study with 1,601 participants, those undergoing DBC faced a PEP rate of 20.7% when they also had high pre-procedure risk, compared to lower rates for non-DBC groups.
- Prophylactic measures, such as combining rectal indomethacin with pancreatic duct stenting, were found to effectively reduce the risk of PEP, even with an increasing number of PD wire passages during DBC.
Introduction: Prophylactic pancreatic stent placement (PSP) is effective for preventing pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP) in high-risk cases, but the optimal technical approach to this intervention remains uncertain.
Methods: In this secondary analysis of 787 clinical trial patients who underwent successful stent placement, we studied the impact of (i) whether pancreatic wire access was achieved for the sole purpose of PSP or naturally during the conduct of the case, (ii) the amount of effort expended on PSP, (iii) stent length, (iv) stent diameter, and (v) guidewire caliber. We used logistic regression models to examine the adjusted association between each technical factor and post-ERCP pancreatitis (PEP).
Seven healthy, physically active men (n = 3) and women (n = 4) (30.7 ± 7.5 years, 172.
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