Publications by authors named "J Scarisbrick"
Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of diseases characterised by abnormal neoplastic T-cell growth in the skin. Mycosis fungoides (MF), the most common CTCL, manifests as erythematous skin patches and/or plaques, tumours or erythroderma. The disease may involve blood, lymph nodes and rarely viscera.
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- * Radiation oncologists must make tailored decisions for patient treatment, but these choices would benefit from more clinical evidence and research.
- * The article calls for a prospective trial to better understand how different radiation doses affect patient outcomes in primary cutaneous lymphoma treatment.
Article Synopsis
- - Mycosis fungoides (MF) and Sézary syndrome (SS) are skin-related lymphomas that can significantly affect quality of life (HRQL), and a study found that patients treated with mogamulizumab reported better HRQL compared to those on vorinostat.
- - A study involving 372 adults with relapsed MF or SS revealed that their HRQL was notably lower than normal averages, particularly affecting their emotional state and functioning due to factors like itchiness and overall health.
- - Key demographic factors such as being female, younger, and having specific health conditions were linked to worse HRQL across different assessments, emphasizing the need to address these issues in patient care.
Article Synopsis
- This project gathered experts to create guidelines for treating a skin condition called pediatric Mycosis fungoides (MF), which is different from how adults are treated.
- They talked about important factors that go beyond just measuring the size of the disease, like itching, how it affects daily life, and feelings of worry or embarrassment.
- The team made 10 recommendations for managing both early and advanced stages of pediatric MF, but they still need more information on how to treat the later stages properly.