A freshwater green microalgal strain was isolated and the lectin was identified in it by a strong hemagglutination activity (HA) assay. Characterization of the algal strain was found to be (MW769776). A single step affinity chromatographic technique was developed to purify lectin (CSL) using guar gum as the affinity matrix.
View Article and Find Full Text PDFBackground: Preterm low birth weight (PLBW) is one of the causes of infant mortality and morbidity. Most of the studies have indicated the periodontal-systemic interlink. The association of periodontal pathogen on pregnancy outcome still stands inconclusive.
View Article and Find Full Text PDFAnidulafungin, a new class of antifungal agent used for the treatment of chronic fungal infections, is derived from Echinocandin B nucleus, an intermediate metabolite of Echinocandin B produced by . The enzyme acylase plays a key role in the bioconversion of Echinocandin B to Echinocandin B nucleus. In the present study, a rapid screening method was used to select an actinomycete capable of producing Echinocandin B acylase.
View Article and Find Full Text PDFLovastatin is a competitive inhibitor of the enzyme hydroxymethyl glutaryl coenzyme A reductase (HMGR) in cholesterol biosynthetic pathway and hence used in the treatment of hyperlipidemia. In a previous study, we report a tropical soil isolate, Aspergillus terreus (KM017963), which produces ample amount of lovastatin than its counterpart that are endophytic in origin. Bioinformatic analysis of whole genome sequence of A.
View Article and Find Full Text PDFCurr Res Environ Appl Mycol J Fungal Biol
July 2017
, a coprophilous basidiomycetous fungus generally called as inky cap mushroom is used as a model organism to study the evolution of fruiting bodies in higher fungi. Herbivorous animal dung is a major source of , as it contains high carbon, nitrogen, and phosphorus elements. Due to the extensive application of in Genetics, Molecular Biology and Microbial Biotechnology it is necessary to explore a suitable inexpensive medium for its cultivation.
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