De novo lipogenesis protects dormant breast cancer cells from ferroptosis and promotes metastasis.

Dormant disseminated tumor cells (DTCs) remain viable for years to decades before establishing a clinically overt metastatic lesion. DTCs are known to be highly resilient and able to overcome the multiple biological hurdles imposed along the metastatic cascade. However, the specific metabolic adaptations of dormant DTCs remain to be elucidated.

Mammographic density and exposure to air pollutants in premenopausal women: a cross-sectional study.

Background: Mammographic density (MD) is a well-established risk factor for breast cancer. Air pollution is a major public health concern and a recognized carcinogen. We aim to investigate the association between MD and exposure to specific air pollutants (SO, CO, NO, NO, NO, PM, PM, and O) in premenopausal females.

Enhancing strategic decision-making in differential games through bifurcation prediction.

Qualitative changes can occur in the dynamics of nonlinear systems even for small parameter variations. Such changes are manifestations of bifurcation in dynamical systems. In the context of differential game theory, bifurcations offer insights into the underlying mechanisms driving strategic interactions and identify transitions between different types of behavior.

Impact of sarcopenic obesity on surgical complications and oncologic outcomes of upper gastrointestinal tumors: a systematic review and meta-analysis.

Sarcopenic obesity (SO) is a new entity whose definition encompasses the diagnosis of overweight in malnourished patients. The aim of the review was to assess the impact of body composition in patients with esophago-gastric tumors (EGT) on perioperative and oncological outcomes. This systematic review was conducted under the PRISMA guidelines.