Elucidation of furanone as ergosterol pathway inhibitor in .

In the era of antiretroviral therapy, the prevalence of Cryptococcal infection among HIV patients in developed countries has decreased considerably. However, ranks top among the critical priority pathogen that affects a wide range of immunocompromised individuals. The threat of is because of its incredibly multifaceted intracellular survival capabilities.

A holistic review on Cryptococcus neoformans.

Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in immunocompromised individuals such as HIV patients, organ transplant patients, hematological malignancies, diabetes patients, etc. The most common invasive fungal pathogens are Candida spp., Aspergillus spp.

Knowledge of Australian primary education providers towards dental avulsion injuries: a cross-sectional study.

Background/aim: The aim of this study was to evaluate the knowledge of school professionals regarding the emergency management of dental avulsion.

Methods: This cross-sectional study utilised a self-administered, pilot-tested questionnaire for school staff from primary schools. Descriptive statistics were used for the analysis - the prevalence and univariate associations between a categorical outcome and the variables under consideration, were evaluated using Pearson's Chi-squared test.

Association of hypoxia inducible factor-1 alpha exon 12 mutation in diabetic patients with and without diabetic foot ulcer.

Hypoxia inducible factor 1 alpha (HIF-1α) is a key regulator of the genes involved in the cellular response to hypoxia. This study aims to determine the HIF-1α gene polymorphism and its association with protein expression in diabetic subjects with and without diabetic foot ulcers (DFU). A total of 529 patients with T2DM (N = 185), DFU (N = 199) and Control (N = 145) were accounted for the study.

Cytotoxicity and Apoptotic Assay in HT-29 Cell Line Using Linn: Leaves Extract.

Background: Linn. (Family ), well-known beneficial medicinal shrub, has been traditionally used for the treatment of various diseases such as leukoderma.

Objective: The aim of the present study is to investigate the efficacy of ethanolic leaves extract for antiproliferative, apoptotic, cell cycle blockade, and wound healing.