Publications by authors named "J Santoyo"

Background: Several scores have been developed to stratify the risk of graft loss in controlled donation after circulatory death (cDCD). However, their performance is unsatisfactory in the Spanish population, where most cDCD livers are recovered using normothermic regional perfusion (NRP). Consequently, we explored the role of different machine learning-based classifiers as predictive models for graft survival.

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In recent years, the age at which liver transplantation is considered indicated has been extended. Currently, age alone is not a contraindication for liver transplantation. Studies are being carried out that reflect the increased survival and similar technical success of transplantation in these patients compared to younger patients.

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Article Synopsis
  • The study evaluates the implementation of an Enhanced Recovery After Surgery (ERAS) protocol in cirrhotic patients undergoing liver resection, as previous research mainly focused on patients with normal liver function.
  • Data was collected from 101 adult patients, with outcomes indicating similar recovery, hospital stay, and complications between cirrhotic and non-cirrhotic patients.
  • Compliance with the ERAS protocol significantly reduced complication rates, showing that using this approach in cirrhotic patients is both feasible and effective, yielding results comparable to those of standard patients.
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  • Reno-portal reconstruction is a surgical option for improving portal flow in liver transplants affected by complete portal thrombosis, especially when collateral veins are present.
  • A 58-year-old man with cirrhosis and significant portal thrombosis underwent surgery, leading to the decision to perform a reno-portal and portoportal anastomosis to enhance blood flow, resulting in a healthy portal flow rate.
  • Post-surgery, the patient showed good recovery and favorable liver function, demonstrating that combined anastomosis techniques can effectively address insufficient portal flow due to a small portal vein.
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  • Active infections in liver transplant recipients pose significant risks due to required immunosuppression, making them an absolute contraindication for the procedure.
  • Despite successful treatments of viral infections like Influenza A in post-transplant patients, no prior cases have shown safe pre-transplant candidates with the virus.
  • The mild symptoms associated with some viral infections, along with available treatments, suggest the potential for reconsidering liver transplants in selected cases with positive outcomes.
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