Publications by authors named "J Santarelli"

Background: Subacute and chronic subdural hematomas are common and frequently recur after surgical evacuation. The effect of adjunctive middle meningeal artery embolization on the risk of reoperation remains unclear.

Methods: In a prospective, multicenter, interventional, adaptive-design trial, we randomly assigned patients with symptomatic subacute or chronic subdural hematoma with an indication for surgical evacuation to undergo middle meningeal artery embolization plus surgery (treatment group) or surgery alone (control group).

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  • Spontaneous splenic rupture is a rare condition usually related to diseases like infectious mononucleosis caused by the Epstein-Barr virus, and it typically lacks an identifiable cause.* -
  • The article discusses a case of a 73-year-old woman who experienced sudden left-sided flank pain, leading to the discovery of a splenic injury requiring emergency surgery and splenectomy.* -
  • Early diagnosis and treatment of spontaneous splenic rupture are crucial, as delays can increase the risk of serious complications, and while some stable patients might be treated non-operatively, long-term outcomes remain uncertain.*
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  • * A successful case of bilateral MMA embolization is reported for a 13-year-old with persistent subdural hematomas after tumor resection, highlighting its potential in pediatric applications.
  • * The literature review indicates that most MMA embolization cases in children involved chronic subdural hematomas and other vascular malformations, suggesting further investigation is needed to establish guidelines for safety and efficacy.
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Background: Evidence regarding the utilization and outcomes of endovascular thrombectomy (EVT) for pediatric ischemic stroke is limited, and justification for its use is largely based on extrapolation from clinical benefits observed in adults.

Methods: Weighted discharge data from the National Inpatient Sample were queried to identify pediatric patients with ischemic stroke (<18 years old) during the period of 2010 to 2019. Complex samples statistical methods were used to characterize the profiles and clinical outcomes of EVT-treated patients.

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Congenital variants of the aortic arch are important to recognize not only for their association with congenital heart disease, vascular rings, and chromosomal abnormalities but also for the purposes of neurointerventional angiography. While many different variants have been reported in the literature, we present two rare cases of an aortic arch variant that, to the best of our knowledge, has not yet been described in the literature- an anteriorly-directed, independent common origin of both carotid arteries from the ascending aorta, with separate subclavian artery trunks originating from the arch.

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