Publications by authors named "J Sangumani"
Purpose: The aim is to validate the third generation Thyrotropin receptor antibody (TRAb) assay for predicting neonatal thyroid dysfunction and adverse pregnancy outcomes in pregnant women with Graves' disease.
Methods: This prospective cohort study was conducted in TRAb positive pregnant women with Graves' disease and their off springs. The primary outcome was to assess different forms of neonatal thyroid dysfunction in relation to maternal and neonatal TRAb levels.
Highly Active Antiretroviral Therapy-associated Lipodystrophy: Pseudo-Cushing's Syndrome.
J Assoc Physicians India
February 2023
Article Synopsis
- Insulin resistance and hyperinsulinemia contribute to polycystic ovary syndrome (PCOS), and the study aimed to compare metformin alone against metformin combined with Myoinositol and d-chiro-inositol in treatment outcomes for PCOS patients.
- Conducted over 6 months, the randomized controlled trial included overweight and obese women aged 18-35 with PCOS, divided into two treatment groups to assess various health parameters.
- Results showed that both treatments improved menstrual cycle regularity, but the myoinositol group had significantly better outcomes in quality of life, while pregnancy rates were similar; other hormonal and metabolic improvements weren't statistically significant.
Aims And Objectives: Clinical, biochemical, and radiological profiles of Addison's disease and to assess the various etiological spectrum of primary adrenal insufficiency (PAI) in adults.
Materials And Methods: A retrospective cohort study was carried out in the Department of Endocrinology, Madurai Medical College, Madurai between January 2014 and January 2021 over a 7-year period.
Inclusion Criteria: All the patients with clinical symptoms and or signs of suspected PAI, such as hyperpigmentation, weight loss, persistent nausea or vomiting, fatigue, and hypotension, were recruited.
Introduction: COVID19* is a new disease with significant mortality risk. Because of the scarcity of the study on factors associated with the mortality in Tamil Nadu present study was done to determine the factors associated with the outcome of the COVID19 patients admitted in a tertiary care hospital, Madurai.
Methodology: 4530 lab confirmed COVID19 patients admitted from March to August 31st 2020; excluding the non-responders or who gave incomplete information were included in the study.