Advancing neutron imaging techniques to highest resolution with fluorescent nuclear track detectors.

Neutron imaging is a nondestructive and noninvasive inspection technique with a wide range of potential applications. However, the fundamentals of this technique still need to be improved, one of which involves achieving micrometer scale or even better resolution, which is a challenging task. Recently, a high-resolution neutron imaging device based on fine-grained nuclear emulsions was developed.

Pulmonary Mycobacterium malmoense Infection in a Patient with Non-small Cell Lung Cancer, Systemic Sclerosis, and Interstitial Pneumonia: A Case Report and Brief Review of the Literature.

A 69-year-old man with systemic sclerosis and interstitial pneumonia presented with an abnormal shadow in the right upper lung lobe. A thoracoscopic needle biopsy was performed on the right upper lobe lesion, and Mycobacterium malmoense was identified by 16S rRNA and rpoB gene sequencing. Surgical treatment was performed to obtain a radical cure, and lung squamous cell carcinoma and M.

Blepharoptosis Associated With the Wearing of Hard Contact Lenses in Keratoconic Eyes.

Keratoconus is a condition that causes progressive thinning and anterior protrusion of the cornea. Because of its irregular astigmatism, mild to moderate keratoconus is corrected with hard contact lenses (HCLs), but blepharoptosis due to the long-term wearing of HCLs is often a problem. In this study, we investigated blepharoptosis in HCL wearers with keratoconus.

Construction of bispecific antibodies by specific pairing between the heavy chain and the light chain using removable SpyCatcher/SnoopCatcher units.

During the production of bispecific antibodies (bsAbs), nonspecific pairing results in low yields of target bsAb molecules, an issue known as the "mispairing problem." Several antibody engineering techniques have been developed to overcome mispairing issues. Here, we introduce "bsAb by external pairing and excision" (BAPE), a novel chain pairing method that induces specific chain pairing by fusing external SpyCatcher/Tag and SnoopCatcher/Tag units.